Dr. Caine, the murdering dentist from the original movie, has escaped from the mental hospital where he has been since being caught. Hoping to resume a normal life, he makes his way to a quiet Midwestern town under a false name and takes on the responsibilities of the town dentist Things are starting to look up for Caine, until the day when he catches his new love in the arms of someone else. Just as in the first movie, this sends him back over the edge and into another homicidal rampage, with his unfortunate patients bearing the brunt of his hostility.
Buried deep beneath the earth for a hundred years Jonathan had to sacrifice his own soul and become a vampire in order to find his true love. Meanwhile, a beautiful young woman, Victoria, wakes from recurring dreams of a time when she was in love. It is clear that Victoria is Jonathan’s true love and when they finally meet, they realize that their souls are forever intertwined. Victoria finds herself caught between her immortal love and her mortal ties. Jonathan has made the ultimate sacrifice for her – his own mortality. Will she now do the same for him?