Two horror segments based on Edgar Allan Poe stories set in and around the city of Pittsburgh. “The Facts in the Case of M. Valdemar” concerns a cheating wife who is trying to scam her dying husband out of millions by having her doctor/hypnotist lover hypnotize the geezer into signing his dough over to her. The old man dies while under hypnosis and is stuck in the limbo between the here and the hereafter. The door to the physical world is opened and the undead attempt to enter it. “Black Cat” is the story of Rodd Usher, an alcoholic photographer/artist, who descends into madness after he kills a stray cat that his live-in girlfriend Annabelle brings home. One murder leads to another, and the complex cover-ups begin.
An anorexic young woman escapes from a psychiatric clinic and meets a young man who wants to help. She is caught and returned to her parents, who are soon beheaded by a garrotting stranger making the rounds about town, apparently striking only when it rains. The orphaned young woman and her new lover launch their own investigation and are endangered when a link is discovered with the victims and a particular operation performed years before.
An ancient urn is found in a cemetery outside Rome. Once opened, it triggers a series of violent incidents: robberies, rapes and murders increase dramatically, while several mysterious, evil-looking young women coming from all over the world are gathering in the city. All these events are caused by the return of Mater Lacrimarum, the last of three powerful witches who have been spreading terror and death for centuries. Alone against an army of psychos and demons, Sarah Mandy, an art student who seems to have supernatural abilities of her own, is the only person left to prevent the Mother of Tears from destroying Rome.
A reporter and a blind retired journalist try to solve a series of murders. The crimes are connected to experiments by a pharmaceutical company in secret research. The two end up becoming targets of the killer.
Roberto, a drummer in a rock band, keeps receiving weird phone calls and being followed by a mysterious man. One night he manages to catch up with his persecutor and tries to get him to talk but in the ensuing struggle he accidentally stabs him. He runs away, but he understands his troubles have just begun when the following day he receives an envelope with photos of him killing the man. Someone is killing all his friends and trying to frame him for the murders…