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Nine friends take a holiday at a Victorian home on a private island and uncover a game that when played brings out the worst in each of them. Jealously, greed, hatred, lust, all of the things they keep buried deep inside themselves rise to the surface and come to a boil.
This darkly comedic drama follows the erotic exploits of Jonathan Barrows, a narcissistic college professor whose sexual fascination with his own body leads him to down a path of increasingly disturbed behavior. Forsaking priests and others who lust for him, Barrows soon pays a high price for his excessive self-love.
How far would you go to confront the demons of your past? After twenty-something Joe plays a seemingly innocent drinking game at a party, he suffers a sudden violent blackout that awakens something sinister within. Much to his horror, they become more frequent in the coming days and bring with them visions of mind-numbing terror. As Joe questions his diminishing sanity, he is met with increasing physical pain that spawns balls of bloodstained flesh from his very body. He must trace his forgotten childhood to learn the savage truth that left him in an orphanage and why now it has returned to haunt him.
Thanks to an auto accident, a parasitic alien manages to get into a hospital. It quickly moves from the crash victim into a candy striper. Among the patients at the hospital are some rather short high school basketball players. It is through them that we watch the events unfold. The infected, or inhabited, candy striper becomes predatory. She goes after men for sex and after women to spread. Infected women develop an incredible sweet tooth and devour anything sweet they can find. The horror then spreads. As the horror takes over more of the hospital and the CDC locks it down, the basketball players and a few friends do everything they can to try and get out of the hospital. But soon it becomes evident that the problem has spread too far. Now if they manage to escape it will only be to delay the inevitable if they cannot halt the spread of aliens before they get out and take over the whole world.